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Diet quality and depression risk
In the SUN cohort, higher adherence to Mediterranean, pro-vegetarian, and AHEI-2010 diet scores tracked with lower risk of incident depression over about 8.5 years.
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What cohort supplied the data?
The SUN Project, a Spanish diet and lifestyle follow-up cohort.
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified
How many participants entered analyses?
15,093 after exclusions.
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified
What was the primary outcome?
Incident depression during follow-up.
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified
Which three diet scores were compared?
MDS, PDP, and AHEI-2010.
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified
What PDP hazard ratio compared extreme quintiles at baseline?
Multivariable HR 0.78 (95% CI 0.64–0.93).
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified
What overall conclusion did authors draw?
Better adherence to the three diet-quality scores linked to lower depression risk in Spanish adults.
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified
How complete was cohort follow-up generally?
Overall retention approaches 90%.
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified
What dose–response pattern did they emphasize?
A threshold effect: substantial reduction from low to moderate adherence, little extra gain thereafter.
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified
How often were questionnaires collected?
Every 2 years by postal or web questionnaires.
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified
Why can’t this study alone guide clinical diet prescriptions for depression?
It is observational, so unmeasured confounding and reverse causation remain possible.
Source: A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project · DOI · quote verified