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Infant diet shapes gut–host immunity
Breast- vs formula-fed infants differ in gut microbiota and host immune gene expression.
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Sample sizes?
6 BF and 6 FF infants.
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified
Intestinal genes tested?
459.
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified
Immunity genes tested?
660.
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified
Microbiome contrast?
Taxa differ by diet.
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified
Phyla note?
~40% Firmicutes and Actinobacteria each in described profile.
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified
Host readout?
Exfoliated epithelial mRNA arrays.
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified
Analysis?
Permutation FDR differential expression.
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified
Limit?
Small cohort; correlative.
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified
Biology lesson?
Diet couples microbes to host immune programs.
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified
bestTopic?
microbiome
Source: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response · DOI · quote verified