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Interdisciplinary frailty RCT
A 12-month multifactorial interdisciplinary program reduced frailty prevalence and improved mobility versus usual care in frail older adults in Sydney.
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What trial design was used?
Single-center randomized controlled trial in frail older people in Sydney.
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified
How long did the intervention last?
A 12-month multifactorial interdisciplinary program after randomization.
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified
What was the absolute frailty difference at 12 months?
14.7 percentage points lower in the intervention group (P = 0.02; NNT 6.8).
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified
How did SPPB change by 12 months?
Controls declined ~0.98 points while intervention gained ~0.52 (between-group 1.44).
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified
What was the sample’s mean age and sex mix?
Mean age 83.3 years; 68% women.
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified
What proportion of eligible people joined?
75% (241 of 322).
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified
Which secondary outcomes were tracked besides frailty?
Hospitalizations, nursing-facility admissions, Barthel disability, and EQ-5D quality of life.
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified
When were assessments scheduled?
Baseline, 3 months, and 12 months after randomization.
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified
Was the frailty difference significant at 3 months?
Between-group frailty differences were significant at 12 months but not at 3 months.
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified
What physiotherapy volume was typical?
Median of 10 face-to-face physiotherapy sessions in the intervention group.
Source: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial · DOI · quote verified