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COVID-19 death risk and comorbidities
In 31,461 US adults with COVID-19, older age, male sex, Black race, and several comorbidities including heart disease predicted higher mortality.
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How many adults entered the mortality analyses?
31,461 patients.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
What was the median age and sex mix?
Median age 50 years; 54.5% female.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
Which comorbidities were most common?
Chronic pulmonary disease (17.5%) and diabetes (15.0%).
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
What share had no listed Charlson comorbidity?
59.5% (18,734) had none recorded.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
Which factors were associated with mortality in conclusions?
Older age, male sex, Black race, MI, HF, dementia, lung/liver/renal disease, metastatic tumour.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
What cardiac message did authors emphasize?
Prior MI or congestive heart failure may influence COVID-19 mortality.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
What data source was used?
TriNetX federated EMR network from US healthcare organisations.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
Why might ethnicity analyses be cautious?
Ethnicity was unknown for a large share of patients.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
Did comorbidity associations vary by age?
Yes—authors noted age-group differences in which comorbidities linked to death.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
What study design was used?
Retrospective cohort analysis of EMRs.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified
How many organisations contributed patients?
24 healthcare organisations.
Source: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis · DOI · quote verified