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HSP90 family across kingdoms

Comparative genomics maps 103 HSP90-family genes across 32 genomes and deep phylogenetic diversity.

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Phylogeny set?

197 sequences / 146 species.

Source: Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms · DOI · quote verified

Richest clade?

Vertebrates (4–16 genes).

Source: Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms · DOI · quote verified

Archaea?

Essentially lacking (one-like exception).

Source: Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms · DOI · quote verified

Role?

Stress response / client folding chaperone.

Source: Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms · DOI · quote verified

New predictions?

12 newly predicted genes.

Source: Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms · DOI · quote verified

Limit?

Sequence survey ≠ client assays.

Source: Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms · DOI · quote verified

Takeaway?

HSP90 expanded differently across kingdoms.

Source: Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms · DOI · quote verified