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Immune transcriptome of bacteria-challenged sea bass
Deep RNA-seq of bacteria-challenged Lateolabrax japonicus reveals innate immune genes.
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What species?
Lateolabrax japonicus (sea bass).
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified
Experimental contrast?
Bacteria-challenged versus mock.
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified
Tissues profiled?
Head kidney and spleen.
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified
What was produced?
Deep transcriptome consensus sequences.
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified
Immune molecules found?
Hepcidin, lysozyme, lectins, chemokines, RAG.
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified
Pathway signal?
Enrichment in immune metabolic/signaling pathways.
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified
Why study fish immunity?
Model immune evolution and disease.
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified
Sequencing tech?
Illumina/Solexa deep RNA-seq.
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified
CDS recovered?
Tens of thousands of reliable coding sequences.
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified
Takeaway?
Infection reshapes teleost innate immune transcriptomes.
Source: Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish · DOI · quote verified