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Coral gene expression in white syndromes
White-syndrome lesions in Acropora hyacinthus show distinct innate-immunity–related expression versus healthy tissue.
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Host species?
Acropora hyacinthus coral.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified
Disease phenotype?
White syndromes with tissue loss.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified
Tissue contrasts?
Disease, adjacent, and healthy.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified
DEG disease vs healthy?
Hundreds of genes pass FDR.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified
Adjacent vs healthy?
Few/no genes pass strict FDR.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified
Immune context?
Corals rely on innate immunity.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified
Method?
RNA-seq differential expression.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified
Pathogen debate?
Vibrio vs host cell-death hypotheses exist.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified
Expression structure?
Disease samples separate in ordination.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified
Takeaway?
Coral lesions rewire innate immune gene expression.
Source: Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus · DOI · quote verified