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Salmon fat-cell differentiation transcriptome
Atlantic salmon adipose SVF cells progress through proliferative then adipogenic expression programs.
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Species?
Atlantic salmon.
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified
Starting cells?
Adipose-derived stromo-vascular fraction.
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified
Differentiation goal?
Mature adipocytes.
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified
Early proliferative stage?
Highest proliferation in first culture days.
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified
Induction timing?
Adipogenic hormones around confluence (~day 7).
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified
Mature phenotype signs?
Large lipid droplets; Oil Red O positive.
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified
Early transcriptome mix?
MSC, immune, and perivascular gene signatures.
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified
Why fish adipose matters?
Aquaculture diets drive visceral fat.
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified
Extracellular SOD trend?
Activity falls across differentiation.
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified
Takeaway?
Fish adipogenesis has staged transcriptional programs.
Source: Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes · DOI · quote verified