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How much do gut bacterial gene contents differ?
Same gut bacterial species can differ widely in gene content across people, shaping functional individuality.
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What need does the study address?
Characterize species gene content in natural habitats.
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified
What ecosystem is studied?
Human intestinal microbiome.
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified
What variation level is key?
Strain variation of the same species across people.
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified
What method was developed?
Gene deletion detection in metagenomic data.
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified
What functional loci example is given?
Polysaccharide utilization loci (PULs).
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified
What community type is handled?
Complex human gut microbial communities.
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified
What forces shape strains in situ?
Natural selection and environmental factors.
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified
What caveat about sample size?
Limited sample sizes.
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified
What phenotypic stake is claimed?
Gene-content differences can cause major phenotypic changes.
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified
What broader microbiome lesson?
Functional individuality can arise within species, not only between species.
Source: Inter-individual differences in the gene content of human gut bacterial species · DOI · quote verified