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Rapid gram-positive blood culture ID
A microarray panel identified Staphylococcus from positive blood cultures with ~99% sensitivity and specificity versus culture.
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How many monomicrobial cultures?
1,157.
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified
Staph sensitivity?
99.4% (840/845).
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified
Staph specificity?
99.7% (310/311).
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified
Most common organisms?
Staphylococcus spp. (73.0%).
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified
Specimen?
Positive blood culture broths.
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified
Index test?
Automated microarray nucleic-acid panel.
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified
Reference?
Conventional culture identification.
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified
Why it matters clinically?
Faster organism/resistance ID from positive bottles.
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified
Limit?
Accuracy ≠ proven outcome benefit of faster results.
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified
Strep share?
About 11.7% of monomicrobial cultures.
Source: Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test · DOI · quote verified