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Gut microbes, blood metabolites, and metabolic traits
In 531 METSIM men, gut microbiota associate with plasma metabolites and metabolic-syndrome-relevant traits.
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How many men were in the microbiome–trait analysis?
531 middle-aged Finnish men.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified
Full METSIM cohort size?
10,197 individuals.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified
What three domains are related?
Gut microbiota, plasma metabolites, and metabolic syndrome traits.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified
Where was METSIM collected?
Kuopio, Eastern Finland.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified
Besides genetics/lifestyle, what factor is emphasized?
Gut microbiota.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified
How can microbes influence host phenotype?
By producing metabolites that affect the host.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified
How is the gut microbiome described?
Complex and metabolically active.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified
Study approach?
Systematic cohort analysis of microbiome and traits.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified
Trait focus?
Factors impacting metabolic disease development.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified
Student takeaway?
Microbiome–metabolite links help explain human metabolic trait variation.
Source: Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort · DOI · quote verified