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Is the gut microbiome the same along the intestine?
Swine mucosal and luminal microbiomes differ by gut section, with distinct diversity patterns and bile-acid/SCFA environments.
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Which phyla dominate swine gut communities here?
Firmicutes, Bacteroidetes and Proteobacteria.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
Do lumen and mucosa communities differ?
Yes—significant richness and α/β-diversity differences by section and niche.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
How do ileal total bile acids compare to large intestine?
About 3-fold higher in the ileum than cecum/colon.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
Why community assembly matters?
Critical for GI homeostasis and host health.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
Does anatomical continuity erase microbiome differences?
No—differences persist despite structural continuity.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
What niches were compared?
Luminal vs mucosa-attached microbiota across gut sections.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
Host model?
Swine intestinal tract.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
What metabolites were profiled alongside microbes?
Bile acids and SCFAs in compartments.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
Are pig and human gut phyla similar at this coarse level?
Authors note similarity to prior pig and human findings.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
Teaching point?
Gut microbiomes are spatially structured by anatomy and niche.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified
What contributes to diversity differences?
Both abundance profiles and presence/absence structure of OTUs.
Source: Spatial Heterogeneity and Co-occurrence of Mucosal and Luminal Microbiome across Swine Intestinal Tract · DOI · quote verified