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As chickenpox shots rose, what happened to shingles?
In Massachusetts, higher childhood varicella vaccine coverage tracked with less varicella but more reported herpes zoster—causality still uncertain.
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What paired trends accompanied rising coverage?
Varicella decreased while herpes zoster increased.
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
How much did toddler coverage rise?
From 48% to 89% among 19–35-month-olds.
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
What survey measured disease occurrence?
Massachusetts BRFSS.
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
How large was the zoster rise 1999–2003?
Age-standardized incidence rose by 2.5 cases per 1,000 (90%).
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
Is vaccination proven to cause rising zoster here?
No—authors say it is only one of several possible explanations.
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
Which virus underlies both diseases?
Varicella-zoster virus targeted by varicella vaccine.
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
What adult disease follows latent infection?
Herpes zoster (shingles).
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
What boosting idea is discussed?
External boosting from exposure to circulating VZV may delay zoster.
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
Where was the study set?
Massachusetts.
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
What does BRFSS stand for in spirit?
Behavioral Risk Factor Surveillance System.
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified
What future zoster prevention do authors anticipate?
A vaccine to prevent herpes zoster and its complications.
Source: The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003 · DOI · quote verified