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How much dementia could prevention still avert?
In Rotterdam cohorts, about one quarter to one third of dementia cases were potentially attributable to modifiable risks—and that share did not shrink over two decades.
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What fraction of dementia was potentially preventable?
About one quarter to one third of cases.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
Did prevention potential decline across decades?
No—it has not declined over the last two decades.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
Which risk class anchors prevention estimates?
Modifiable risk factors, especially cardiovascular risks/diseases plus education.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
What epidemiologic measure quantifies prevention potential?
Population attributable risk (PAR).
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
Which cohort platform was used?
The prospective, population-based Rotterdam Study.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
What outcome is being prevented?
Dementia incidence.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
What time span frames the comparison?
Across two decades of cohorts.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
What do authors urge given stable PAR?
Public health interventions are urgently needed.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
Which vascular/educational levers are named in the key claim?
Cardiovascular risk factors and diseases and educational level.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
Why is PAR not the same as proven trial efficacy?
It estimates theoretical preventable fraction under assumptions, not a tested intervention package.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified
What broader dementia burden argument do authors make?
Prevention is currently a main option to diminish dementia burden.
Source: The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study · DOI · quote verified