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How broadly does smoking raise heart and vessel disease risk?

In a large Australian cohort, current smoking raised risk across nearly all CVD subtypes—especially peripheral arterial disease—and quitting lowered risk.

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How many major CVD events occurred in follow-up?

27,511 major CVD events over 1.35 million person-years.

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified

What was the PAD relative risk in current smokers?

About 5.06 versus never smokers.

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified

How did current smokers’ broad CVD risk compare to never smokers?

Significantly increased across major CVD groupings.

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified

What follow-up person-time was accumulated?

1.35 million person-years (mean ~7.4 years).

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified

What happens with quitting according to authors?

Quitting reduces the risk.

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified

Which cohort supplied participants?

The 45 and Up Study in Australia.

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified

How do past smokers generally compare?

Former smokers showed intermediate risk between current and never smokers.

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified

Which acute coronary outcome is highlighted among elevated risks?

Acute myocardial infarction.

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified

What less classic CVD subtype do authors newly emphasise?

Paroxysmal tachycardia risk linked to smoking.

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified

Why does low current smoking prevalence still matter?

Smoking still accounts for a substantial share of premature CVD in an established epidemic setting.

Source: Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study · DOI · quote verified