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LA air toxics, especially PAHs, track preterm birth

In Los Angeles, entire-pregnancy PAHs associated with ~30% higher preterm-birth odds; ammonium nitrate PM2.5 and several traffic markers also raised odds.

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What was preterm prevalence in the study population?

9.2%.

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified

Which pollutants showed ~30% odds increases?

Benzo(g,h,i)perylene and total PAHs; benzo(a)pyrene about 13%.

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified

Why were PAH estimates less precise?

PAHs were measured at only two stations and for shorter times (smallest samples).

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified

What other PM components raised preterm odds per IQR?

Ammonium nitrate PM2.5 plus 9–13% increases for benzene, diesel PM2.5, OC, EC, and biomass-burning PM2.5.

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified

What did authors conclude about PAHs?

PAHs are pollutants of special concern; non-traffic PAH sources also contributed.

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified

How large was the source birth file before exclusions?

n = 276,891 from the California Department of Health.

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified

Who was over-represented near MATES stations?

Younger, Hispanic, Mexico-born, less educated mothers more often on Medi-Cal.

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified

How many exposure information sources were used?

Three different exposure information sources.

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified

What analysis modeled preterm odds?

Single- and multiple-variable conditional logistic regression with IQR ORs.

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified

Did ammonium nitrate suggest a role beyond primary traffic?

Yes—the secondary PM2.5 component suggested secondary pollutants also matter.

Source: Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California · DOI · quote verified