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Does light control fungal cellulase genes?
Neurospora photoreceptors WC-1, WC-2 and VVD influence cellulase expression; light-modulated cellulase regulation is conserved in filamentous fungi.
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Which photoreceptors influence cellulase expression?
WC-1, WC-2 and VVD.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
Is light-modulated cellulase expression unique?
No—authors conclude it is a conserved phenomenon in filamentous fungi.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
Why is Neurospora a good model here?
Best-studied organism for light response and circadian rhythms.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
What enzymes are modulated?
Cellulolytic / cellulase enzymes.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
How did they follow up transcriptional hits?
Evaluated mutant phenotypes of differentially regulated genes in wc-1 backgrounds.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
Proposed ecological rationale?
Evolutionary advantage in the natural habitat.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
Teaching point?
Light sensors can gate metabolic enzyme expression, not only development.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
Photoreceptors act with what?
Cognate signalling cascades affecting many physiological targets.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
Organism?
Neurospora crassa.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
Best topic?
Circadian/light biology intersecting gene expression.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified
What process do cellulases enable?
Breakdown of cellulose for carbon acquisition.
Source: Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa · DOI · quote verified