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iCBT for depression in diabetes

Unmodified clinician-supported iCBT beat treatment-as-usual on depression, anxiety, distress, and diabetes-specific distress in adults with diabetes.

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What population was studied?

Adults with diabetes mellitus and clinically relevant depression.

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

What trial comparison was used?

iCBT versus treatment-as-usual (TAU) wait comparison.

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

How many were randomized?

106 people (49 iCBT, 57 TAU).

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

What was the depression between-group effect?

Moderate Hedges g=0.78 on PHQ-9 favoring iCBT.

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

What was the anxiety between-group effect?

Hedges g=0.72 on GAD-7 favoring iCBT.

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

Did diabetes-specific distress improve?

Yes—large between-group effect on PAID (reported with other significant outcomes).

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

What adherence rate was reported?

66% completed all six lessons (27/41).

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

How did reliable improvement compare?

51% iCBT vs 18% TAU showed reliable PHQ-9 improvement.

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

Was the iCBT program diabetes-specific?

No—authors highlight an unmodified depression iCBT program.

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

What glycemic result is important to remember?

Between-group HbA1c effect was small/nonsignificant in the reported contrasts.

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified

Why does this matter clinically?

Depression in diabetes worsens self-management and outcomes; scalable iCBT may be a treatment option.

Source: Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial · DOI · quote verified